pH-Triggered Echogenicity and Contents Release from Liposomes
نویسندگان
چکیده
منابع مشابه
pH-Triggered Echogenicity and Contents Release from Liposomes
Liposomes are representative lipid nanoparticles widely used for delivering anticancer drugs, DNA fragments, or siRNA to cancer cells. Upon targeting, various internal and external triggers have been used to increase the rate for contents release from the liposomes. Among the internal triggers, decreased pH within the cellular lysosomes has been successfully used to enhance the rate for releasi...
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Introduction Non, or minimally, invasive in vivo visualization of drug release triggered by externally-applied physical stimuli, like heating, light or ultrasound (US) is an emerging topic in molecular medicine. As far as US is concerned, most of the published investigations were performed using nanoor micro-bubbles in which the presence of the gas-filled core makes cavitation (and US detection...
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ژورنال
عنوان ژورنال: Molecular Pharmaceutics
سال: 2014
ISSN: 1543-8384,1543-8392
DOI: 10.1021/mp500186a